![[narrator] Remember the worm and how we mutated its DAF-Two gene?](https://clip.cafe/img800/narrator-remember-the-worm-and-how-mutated-daf-two-gene.jpg)
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[narrator] Remember the worm
and how we mutated its DAF-Two gene? Metformin actually acts
on the human version of that same gene, regulating insulin. And works through other molecular
mechanisms we don't totally understand. The US Federal Drug Administration
approved a metformin trial as a possible treatment
for age-related diseases, not for aging itself, because the FDA doesn't recognize aging
as something that's treatable. But if the results come back positive, that might change,
opening the floodgates for more research. I'm very optimistic
that this is going to be accelerated, and that the next decade is really going
to be the turning point to target aging
and how we mutated its DAF-Two gene? Metformin actually acts
on the human version of that same gene, regulating insulin. And works through other molecular
mechanisms we don't totally understand. The US Federal Drug Administration
approved a metformin trial as a possible treatment
for age-related diseases, not for aging itself, because the FDA doesn't recognize aging
as something that's treatable. But if the results come back positive, that might change,
opening the floodgates for more research. I'm very optimistic
that this is going to be accelerated, and that the next decade is really going
to be the turning point to target aging
Full Transcript
00:00:01.000 --> 00:00:04.504
[narrator] Remember the worm
and how we mutated its DAF-Two gene?
00:00:05.996 --> 00:00:09.003
Metformin actually acts
on the human version of that same gene,
00:00:09.384 --> 00:00:10.593
regulating insulin.
00:00:11.052 --> 00:00:15.264
And works through other molecular
mechanisms we don't totally understand.
00:00:16.683 --> 00:00:20.395
The US Federal Drug Administration
approved a metformin trial
00:00:20.478 --> 00:00:23.106
as a possible treatment
for age-related diseases,
00:00:23.189 --> 00:00:25.001
not for aging itself,
00:00:25.108 --> 00:00:28.861
because the FDA doesn't recognize aging
as something that's treatable.
00:00:28.945 --> 00:00:31.489
But if the results come back positive,
00:00:31.781 --> 00:00:36.244
that might change,
opening the floodgates for more research.
00:00:36.327 --> 00:00:39.914
I'm very optimistic
that this is going to be accelerated,
00:00:40.248 --> 00:00:45.253
and that the next decade is really going
to be the turning point to target aging.
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Movie Summary
A documentary series that looks to explore the big questions of today.
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