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And that mutation causes a kink in the protein
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Human Nature

And that mutation causesa kink in the protein that prevents itfrom folding properly

And that mutation causes
a kink in the protein that prevents it
from folding properly

Full Transcript

00:00:01.000 --> 00:00:02.915
-And that mutation causes a kink in the protein
00:00:02.958 --> 00:00:06.179
that prevents it from folding properly.
Duration
6 seconds
Views
23
Timestamp in Movie
00:06:09
Uploaded
Jun 11, 2025
Genres
documentary
Production
Sandbox Films,News and Guts Films,The Wonder Collaborative

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Movie Summary

A breakthrough called CRISPR opens the door to curing diseases, reshaping the biosphere, and designing our own children. A provocative exploration of its far-reaching implications, through the eyes of the scientists who discovered it
If your folding structure of a protein is disrupted, - Human Nature 00:07
If your folding structure of a protein is disrupted,
It causes the red blood cell - Human Nature 00:07
It causes the red blood cell
-It becomes very stiff, and it can't squeeze through - Human Nature 00:17
-It becomes very stiff, and it can't squeeze through
In Africa, the life expectancy - Human Nature 00:09
In Africa, the life expectancy
In the U.S., it's the early to mid-40s. - Human Nature 00:04
In the U.S., it's the early to mid-40s.
What do you say to a kid that their life is gonna be-- - Human Nature 00:08
What do you say to a kid that their life is gonna be--
Makes me very nervous. - Human Nature 00:06
Makes me very nervous.
David can go from crazy teenager, - Human Nature 00:12
David can go from crazy teenager,
"This hurts. - Human Nature 00:05
"This hurts.
You're having a sickle cell crisis." - Human Nature 00:15
You're having a sickle cell crisis."
This is David's old red blood cells. - Human Nature 00:04
This is David's old red blood cells.
It's a genetic disorder, - Human Nature 00:07
It's a genetic disorder,
We just didn't have the tools - Human Nature 00:07
We just didn't have the tools
-Deoxyribonucleic acid, or DNA for short, - Human Nature 00:08
-Deoxyribonucleic acid, or DNA for short,
Each living thing has its unique DNA - Human Nature 00:08
Each living thing has its unique DNA
If we understood the structure of genes, - Human Nature 00:14
If we understood the structure of genes,
The work that Paul Berg did, - Human Nature 00:06
The work that Paul Berg did,
This dream of gene therapy - Human Nature 00:12
This dream of gene therapy
The hope is that the isolation of the gene - Human Nature 00:06
The hope is that the isolation of the gene
Scientists are working on genetic cures - Human Nature 00:06
Scientists are working on genetic cures