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The letters in the RNA allow Cas9
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Human Nature

The letters in the RNAallow Cas9 to find a unique DNA sequence

The letters in the RNA
allow Cas9 to find a unique DNA sequence

Full Transcript

00:00:01.000 --> 00:00:04.046
The letters in the RNA allow Cas9
00:00:04.009 --> 00:00:08.137
to find a unique DNA sequence.
Duration
8 seconds
Views
16
Timestamp in Movie
00:29:59
Uploaded
Jun 11, 2025
Genres
documentary
Production
Sandbox Films,News and Guts Films,The Wonder Collaborative

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Movie Summary

A breakthrough called CRISPR opens the door to curing diseases, reshaping the biosphere, and designing our own children. A provocative exploration of its far-reaching implications, through the eyes of the scientists who discovered it
Bacteria were programming this thing all the time - Human Nature 00:09
Bacteria were programming this thing all the time
But because it's using these little RNA molecules, - Human Nature 00:08
But because it's using these little RNA molecules,
RNA molecules are trivial to make - Human Nature 00:07
RNA molecules are trivial to make
And I can cut any DNA I want just by changing this-- - Human Nature 00:06
And I can cut any DNA I want just by changing this--
It was clearly a useful tool, - Human Nature 00:06
It was clearly a useful tool,
I was thinking about all the cool experiments - Human Nature 00:05
I was thinking about all the cool experiments
I wasn't thinking about, - Human Nature 00:12
I wasn't thinking about,
In my left hand here, I have purified Cas9 nuclease, - Human Nature 00:14
In my left hand here, I have purified Cas9 nuclease,
It's actually millions of Cas9 molecules, - Human Nature 00:08
It's actually millions of Cas9 molecules,
I have to say it didn't immediately hit me - Human Nature 00:11
I have to say it didn't immediately hit me
You know, it was real. - Human Nature 00:05
You know, it was real.
You can actually use CRISPR in humans to change DNA. - Human Nature 00:05
You can actually use CRISPR in humans to change DNA.
Here's a copy of a human gene. - Human Nature 00:05
Here's a copy of a human gene.
You give it to Cas9 and put it inside human cells. - Human Nature 00:06
You give it to Cas9 and put it inside human cells.
It runs away, finds that DNA, and cuts it. - Human Nature 00:04
It runs away, finds that DNA, and cuts it.
-Before CRISPR, we were getting 1% to 2% correction. - Human Nature 00:05
-Before CRISPR, we were getting 1% to 2% correction.
This could really cure a patient. - Human Nature 00:07
This could really cure a patient.
-I think it's gonna help a lot of people, - Human Nature 00:10
-I think it's gonna help a lot of people,
And I know so many other people - Human Nature 00:07
And I know so many other people
He...uh, had leukemia. - Human Nature 00:05
He...uh, had leukemia.