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When Cas9 polices the intercellular neighborhood
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Human Nature

When Cas9 polices theintercellular neighborhood for invasions,it literally carries a copy...

When Cas9 polices the
intercellular neighborhood for invasions,
it literally carries a copy of that "Most Wanted"
poster with it, asking everyone that comes in, "Excuse me

Full Transcript

00:00:01.000 --> 00:00:04.873
When Cas9 polices the intercellular neighborhood
00:00:04.917 --> 00:00:09.051
for invasions, it literally carries a copy
00:00:09.001 --> 00:00:13.036
of that "Most Wanted" poster with it,
00:00:13.403 --> 00:00:17.407
asking everyone that comes in, "Excuse me.
Duration
17 seconds
Views
13
Timestamp in Movie
00:28:14
Uploaded
Jun 12, 2025
Genres
documentary
Production
Sandbox Films,News and Guts Films,The Wonder Collaborative

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Movie Summary

A breakthrough called CRISPR opens the door to curing diseases, reshaping the biosphere, and designing our own children. A provocative exploration of its far-reaching implications, through the eyes of the scientists who discovered it
Do you contain an exact match - Human Nature 00:08
Do you contain an exact match
-The thing about Cas9 that struck me at the time - Human Nature 00:13
-The thing about Cas9 that struck me at the time
As a tool, right, you could immediately see - Human Nature 00:07
As a tool, right, you could immediately see
I will never forget - Human Nature 00:20
I will never forget
Cas9 cuts DNA based on an instruction that it carries, - Human Nature 00:13
Cas9 cuts DNA based on an instruction that it carries,
-RNA, I think about it as DNA's chemical cousin. - Human Nature 00:05
-RNA, I think about it as DNA's chemical cousin.
Like DNA, it has four letters, - Human Nature 00:11
Like DNA, it has four letters,
The letters in the RNA allow Cas9 - Human Nature 00:08
The letters in the RNA allow Cas9
Bacteria were programming this thing all the time - Human Nature 00:09
Bacteria were programming this thing all the time
But because it's using these little RNA molecules, - Human Nature 00:08
But because it's using these little RNA molecules,
RNA molecules are trivial to make - Human Nature 00:07
RNA molecules are trivial to make
And I can cut any DNA I want just by changing this-- - Human Nature 00:06
And I can cut any DNA I want just by changing this--
It was clearly a useful tool, - Human Nature 00:06
It was clearly a useful tool,
I was thinking about all the cool experiments - Human Nature 00:05
I was thinking about all the cool experiments
I wasn't thinking about, - Human Nature 00:12
I wasn't thinking about,
In my left hand here, I have purified Cas9 nuclease, - Human Nature 00:14
In my left hand here, I have purified Cas9 nuclease,
It's actually millions of Cas9 molecules, - Human Nature 00:08
It's actually millions of Cas9 molecules,
I have to say it didn't immediately hit me - Human Nature 00:11
I have to say it didn't immediately hit me
You know, it was real. - Human Nature 00:05
You know, it was real.
You can actually use CRISPR in humans to change DNA. - Human Nature 00:05
You can actually use CRISPR in humans to change DNA.